What causes protein in urine?


The presence of protein in urine, a condition known as proteinuria, can be caused by various factors. Proteinuria is not a disease itself but rather a symptom of an underlying health issue. Here are some possible causes of protein in urine:

  1. Kidney disorders: The most common cause of proteinuria is kidney-related conditions. These can include glomerulonephritis (inflammation of the kidney’s filtering units), diabetic nephropathy (kidney damage due to diabetes), and nephrotic syndrome (a condition that causes the kidneys to leak large amounts of protein).
  2. High blood pressure: Uncontrolled hypertension can damage the blood vessels in the kidneys, leading to protein leakage into the urine.
  3. Infections: Certain infections, such as urinary tract infections (UTIs) and kidney infections, can cause temporary proteinuria.
  4. Diabetes: Chronic high blood sugar levels in diabetes can damage the kidneys over time, leading to proteinuria.
  5. Autoimmune diseases: Conditions like lupus (systemic lupus erythematosus) and rheumatoid arthritis can affect the kidneys and result in proteinuria.
  6. Medications and toxins: Certain medications, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and some antibiotics, as well as exposure to certain toxins, can cause kidney damage and proteinuria.
  7. Congestive heart failure: When the heart fails to pump blood effectively, it can cause fluid buildup and increased pressure in the blood vessels, leading to kidney damage and proteinuria.

It’s important to note that temporary proteinuria can also occur due to factors such as intense exercise, fever, stress, or dehydration. However, persistent or significant proteinuria should be evaluated by a healthcare professional to determine the underlying cause and appropriate treatment.

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