Is progeria a genetic disorder?

FAQ

Yes, progeria is indeed a genetic disorder. It is also known as Hutchinson-Gilford progeria syndrome (HGPS) and is an extremely rare genetic condition characterized by rapid aging in children. Progeria is caused by a mutation in the LMNA gene, which provides instructions for making a protein called lamin A. This mutation leads to the production of an abnormal form of lamin A known as progerin.

Progerin builds up in the nucleus of cells and disrupts the normal functioning of the cell, leading to the characteristic symptoms of progeria. These symptoms include growth failure, loss of body fat and hair, wrinkled skin, joint stiffness, cardiovascular problems, and a shortened lifespan. It is important to note that progeria is not an inherited disorder in the traditional sense, as it usually occurs as a result of a spontaneous mutation rather than being passed down from parents to their children. However, it is a genetic disorder because it is caused by a specific mutation in the LMNA gene.

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