Is ESR and CRP elevated in lupus?

Yes, both erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) levels can be elevated in lupus, although they are not specific to lupus and can also be elevated in other conditions. ESR measures the rate at which red blood cells settle to the bottom of a test tube over a certain period of time, and high levels can indicate inflammation in the body. CRP is a protein produced by the liver in response to inflammation, and elevated levels can also indicate inflammation. In lupus, these markers can be useful in monitoring disease activity and response to treatment, but they are not diagnostic for lupus and must be interpreted in the context of other clinical and laboratory findings.