Yes, you can wear clothes after applying permethrin cream. Permethrin is a topical cream that is absorbed into the skin and does not require any special clothing or covering. Once the cream has been applied and absorbed into the skin, it is safe to wear regular clothing. However, it is recommended to avoid tight-fitting clothing or excessive rubbing of the area to prevent the cream from being rubbed off. It is also important to follow the instructions on the label and use the cream as directed by your healthcare provider.