Can cancer run in the family?

FAQ

Yes, cancer can run in families. While most cancers are not directly inherited, certain genetic mutations or predispositions can increase the risk of developing cancer within a family. These genetic mutations can be passed down from generation to generation and increase the likelihood of developing cancer.

There are two main types of familial cancers:

  1. Hereditary cancers: These are caused by specific gene mutations that are passed down from a parent to their child. Examples of hereditary cancers include hereditary breast and ovarian cancer syndrome (caused by mutations in the BRCA1 and BRCA2 genes) and Lynch syndrome (caused by mutations in genes such as MLH1, MSH2, MSH6, and PMS2). Individuals with these mutations have a higher risk of developing certain types of cancer compared to the general population.
  2. Familial cancers: These are cancers that occur more frequently in families than in the general population, but do not have a clear genetic mutation associated with them. Familial cancers may be influenced by a combination of genetic, environmental, and lifestyle factors within a family.

It’s important to note that having a family history of cancer does not necessarily mean that an individual will develop cancer. It simply means that their risk may be higher compared to those without a family history of cancer. Regular screenings, genetic testing, and lifestyle modifications can be important steps in managing the risk of cancer in families with a history of the disease. If you have concerns about cancer running in your family, it’s recommended to consult with a healthcare professional or a genetic counselor for personalized information and guidance.

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